Dr. Charles Chung is an Associate Professor of Physiology at Wayne State University with a broad training in physiology and biomechanics. His PhD thesis analyzed human ultrasound and pressure-volume data to provide improved quantification of cardiac diastolic function. The models used help show the balance between myocardial stiffness and crossbridge relaxation. He also has training in molecular biology and integrative physiology, using mouse and rat models to investigate how elastic proteins (titin, extracellular matrix) and crossbridges modify diastolic function.

His lab is investigating clinically translatable and basic science problems in diastolic function, using integrative muscle physiology methods. The overall goals are to 1) determine targets for pharmacologic improvement of cardiac performance and/or 2) determine improved non-invasive measures of cardiac function to assist in care.