Jonathan Brestoff

Jonathan Brestoff, MD, PhD, MPH

Assistant Professor
Department of Pathology and Immunology
Washington University School of Medicine

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Dr. Brestoff received his MD/PhD from University of Pennsylvania with Dr. David Artis, where his research identified a role for Group 2 innate lymphoid cells (ILC2s) in promoting beige fat biogenesis (Brestoff et al., Nature, 2015; Brestoff & Artis, Cell, 2015). He recompleted residency in Clinical Pathology at Washington University School of Medicine, during which time he pioneered studies with Dr. Steven L. Teitelbaum and later in his own lab on cell-to-cell transfer of mitochondria in regulating energy homeostasis (Brestoff et al., Cell Metabolism, 2021; Borcherding/Jia et al., Cell Metabolism, In Press). As a recipient of the NIH Director’s Early Independence Award and Burroughs Wellcome Fund Career Scientists Award, Dr. Brestoff started his independent laboratory at WashU as Assistant Professor of Pathology and Immunology in 2019, leading a research program studying intercellular mitochondria transfer and how the immune system regulates metabolic adaptation to nutrient stress.