Dr. Smith joined Biomodels in 2017 after completing her postdoctoral work at Massachusetts General Hospital. Her work focused on understanding the relationship between checkpoint inhibitor expression patterns and the functional capabilities of tumor-infiltrating lymphocytes. Nicole received her Ph.D. from Boston University School of Medicine in 2016, where she developed a novel murine model that enabled the study of heterotypic adaptive immune memory responses, and using this model identified a novel lung localization pattern for antigen-specific, tissue-resident memory Th17 cells. Dr. Smith is interested in model development and diverse pre-clinical indications, currently focusing on IBD, arthritis, and mucositis.