Targeting Proteomics to Decipher Biology for the Drug Development Pipeline
Dr. Jeffrey Silva explores the role of mass spectrometry-based proteomics on drug discovery, disease mechanisms, and biomarker identification.
#ExpertAnswers: Agenor Limon on the Electrophysiology of Human Native Receptors
Agenor Limon discusses reactivation and microtransplantation of synaptic receptors from frozen human brain samples into xenopus oocytes to evaluate the relationship between synaptic activity and behavioral abnormalities.
Electrophysiology of Human Native Receptors in Neurological and Mental Disorders
Dr. Agenor Limon presents research integrating functional metrics with large anatomical, transcriptomic, and proteomic datasets to evaluate the relationship between synaptic E/I ratio and behavioral abnormalities across postmortem intervals and brain banks.
Plasma Proteomics: The Next Frontier of Biomarker Discovery in the Precision Medicine Era
Plasma proteomics is increasingly recognized as a fundamental approach to accelerate biomarker discovery and drug development, taking precision medicine to the next level.
#ExpertAnswers: Oliver Bernhardt and Andreas-David Brunner on Biological Insights with DIA Proteomics
In this episode of Expert Answers join Oliver Bernhardt and Andreas-David Brunner as they answer questions from a recent webinar about how data independent acquisition has become the method of choice for large scale proteomics.
Spectronaut: Expand Biological Insights with DIA Proteomics
Data-independent acquisition (DIA) has become the method of choice for large-scale discovery proteomics. Its application for single-cell analysis promises to be more sensitive, robust, and reproducible than other proteomic approaches but is still a fairly unexplored territory.
