Agenor Limon discusses reactivation and microtransplantation of synaptic receptors from frozen human brain samples into xenopus oocytes to evaluate the relationship between synaptic activity and behavioral abnormalities.
Dr. Agenor Limon presents research integrating functional metrics with large anatomical, transcriptomic, and proteomic datasets to evaluate the relationship between synaptic E/I ratio and behavioral abnormalities across postmortem intervals and brain banks.
In this episode of Expert Answers join Oliver Bernhardt and Andreas-David Brunner as they answer questions from a recent webinar about how data independent acquisition has become the method of choice for large scale proteomics.
Data-independent acquisition (DIA) has become the method of choice for large-scale discovery proteomics. Its application for single-cell analysis promises to be more sensitive, robust, and reproducible than other proteomic approaches but is still a fairly unexplored territory.