Barry Setlow, PhD is a Professor in the Department of Psychiatry at the University of Florida College of Medicine, and a member of the University of Florida Center for Addiction Research and Education.

His lab uses rodent models to investigate the behavioral and neural mechanisms supporting cognitive and motivational functions, both in their normal operation and in models of various neuropsychiatric conditions. In particular, much of his research focuses on cost-benefit decision making (situations involving choices between small, low-cost vs. large, high-cost rewards), and how such decision making is altered in the context of drugs of abuse.

He and his laboratory team employ a combination of behavioral, pharmacological, optical, and biochemical approaches in their research, with the long-term goal of developing approaches to facilitate adaptive decision making and reduce the burden of neuropsychiatric disease.