Protocol Preview: Long-read sequencing, Nature’s Method of the Year
Nature Methods declared "Long-Read Sequencing" their Method of the Year for 2022, but what exactly makes this technique worthy of such a title?
Protocol Preview: a Ferret Model of Respiratory Inflammation
While rodents have long been used to model many human diseases, their anatomical, physiological, and immunological differences from humans cannot be ignored when modeling respiratory inflammation. Recently, Khoury et al. demonstrated how ferrets can be used to model inflammatory respiratory disease and injury, which we review in this blog post.
Protocol Preview: Creating an Artificial Human Thymus in Mice
The majority of treatments for immunodeficiencies are temporary fixes, in part due to a lack of preclinical models that can accurately predict immune responses in humans. However, a novel model recently published in Nature Methods has potential to greatly improve future immune response studies, which we review in this blog post.