Join Louise Parr-Brownlie, PhD and Conor Underwood, PhD for a review of implantable optogenetics to replace deep brain stimulation, a surgical procedure overview, and a discussion about the impact of acute optogenetic stimulation for the treatment of Parkinson's disease in a rat model.
Dr. Fiona Harrison, discusses how vitamin C deficiency and exposure to toxins can impact glutamate uptake and clearance, and how even small changes in neural signaling can be detected by monitoring EEG activity and correlated with performance in learning and memory tasks.
Dr. Fiona Harrison discusses how dietary deficiency and exposure to toxins can impact glutamate uptake and clearance, and the subsequent changes in neural signaling can be detected through altered EEG activity and performance on learning and memory tasks.
Dr. Janos Groh discusses how neuroinflammation amplifies neural damage and disease outcome in models of various disorders, and the value of monitoring the retinotectal system to assess neural disease progression and associated treatment efficacy.
Experts discuss an innovative and scalable home cage monitoring solution called Digital Ventilated Cage (DVC), showing how it can be used to study neurodegenerative diseases and monitor biorhythmicity of small rodents.
In this episode of Expert Answers, Dr. Carl Petersen and Alexei Verkhratsky discuss astrocyte-mediated homeostatic control of the central nervous system, and how optical and 2-photon microscopy can be used for functional neuroimaging.
In this episode of Expert Answers, Drs. Subramanian & Enzmann share case studies and experimental data from various applications using a newly developed automated system to measure vision based on the optomotor reflex.
A growing body of evidence suggests that Home Cage Monitoring studies are becoming key tools for in vivo animal research for three main reasons: reduction in animal distress thereby increasing welfare, minimization of biases (wanted and unwanted), and increased reproducibility of data.
Experts discuss the use of a novel movement responsive rodent caging system as a means to minimize animal stress and enable unique discovery in many research applications, namely neuroscience, animal behaviour, drug discovery and cardiometabolic disease.
Five experts from the University of Bristol, the German Center for Neurodegenerative Diseases, and the Hungarian Academy of Sciences answer questions from a webinar where they present methodology and research findings from neurophysiological studies in head-fixed, behaving mice.