Translational Applications of MiniPDX: An In Vivo Organoid Assay in New Drug R&D
Join Dr. Danyi Wen as she describes a novel drug efficacy test using Patient Derived Xenograft (PDX) samples to measure drug efficacy and identify therapeutic candidates in personalized oncology treatments.
#ExpertAnswers: Jonas Treebak and Alexander Bartelt on Metabolic Adaptations
In this episode of #ExpertAnswers join Dr. Jonas Treebak and Dr. Alexander Bartelt as they answer questions from a recent [...]
#ExpertAnswers: Sue Bodine on Aging Science
Join Sue Bodine, PhD as she answers questions from a recent webinar that focuses on the decline in muscle mass with aging and the role that innervation plays in muscle atrophy.
Continuous Glucose Monitoring and Glycemic Variability in Pregnancy
Join Caroline Wuyts, MSc for a deep dive into her research on pregnancy and monitoring glucose availability throughout the reproductive timeline of a mouse model.
#ExpertAnswers: Stefano Gaburro and Brun Ulfhake on Aging Science
Join Stefano Gaburro and Brun Ulfhake as they present methods of caged rodent monitoring and better animal welfare that will lead to improved studies of neurodegenerative disease models.
IR Photorefraction and IR Photokeratometry – Measuring Refractive State and Corneal Curvature in Animals and Humans
Prof. Frank Schaeffel discusses the optical principles, image processing algorithms, calibration, and potential pitfalls within IR photorefraction and IR photokeratometry.
Metabolic Adaptations: The Physiology of Cold Acclimatization and Exercise in Rodent Models
Join Jonas Treebak, PhD and Alexander Bartelt, PhD for a deep dive into the physiological mechanisms underlying metabolic adaptations to exercise training and cold exposure.
Cardiac Glucose Metabolism: Heart Failure in Diabetes and Aging
Join Dr. Dale Abel for a deep dive into the mechanisms underlying heart failure in aging and diabetes.
#ExpertAnswers: Dudley Lamming on Aging Science
Join Dudley Lamming, PhD an Associate Professor at the University of Wisconsin-Madison, as he answers questions from a recent webinar that focuses on his research involving how diets can affect metabolic health and longevity.
#ExpertAnswers: Caroline Williams and Eric Riddell on Ecophysiology and Climate Change
Caroline Williams, PhD and Eric Riddell, PhD answer questions from a recent webinar where they discuss their research involving climate change and the ecophysiological effects of changing global temperatures on organismal biology and survival.
Echolocation with Light: A New Form of Active Sensing in Fish?
Prof. Nico K. Michiels discusses how weak light reflections, during active photolocation, in the pupils of predator and prey species can be strong enough to be perceptible by the initial light sender.
#ExpertAnswers: Christian Schnell on Pharmacology Studies in Oncology Research
Christian Schnell, Associate Director of Oncology at Novartis in Basel, answers questions on PK-PD assessment and corresponding antitumor activity in pharmacology studies for oncology research.
#ExpertAnswers: Rizwan Qaisar & Matthew Borkowski on Aging Science
In this episode of Expert Answers, Dr. Rizwan Qaisar and Matthew Borkowski, focus on the experimental protocols used for measuring muscle function and mechanics for in vivo and in vitro research.
#ExpertAnswers: Andrea Benucci on Decision Making Behavior in Mice
In this episode of Expert Answers, Dr. Andrea Benucci discusses a setup developed in his laboratory for high-throughput behavioral training of mice based on voluntary head fixation.
#ExpertAnswers: Angel Moreno on Optogenetics and the Cardiac Autonomic System
This episode of Expert Answers features Dr. Angel Moreno discussing new ways to restore normal cardiac rhythm after a sudden onset of arrhythmia.
#ExpertAnswers: Charlotte Peterson & Jack Guralnik on Aging Science
In this episode of Expert Answers, Dr. Jack Guralnik and Dr. Charlotte Peterson answer questions about sarcopenia, the physiological mechanisms underlying the disease, and the current avenues of treatment and assessment.
#ExpertAnswers: Christopher Axelrod & Sander Kooijman on Rodent Models of Pharmacotherapy and Chronotherapy
In this episode of Expert Answers, Christopher Axelrod and Dr. Sander Kooijman discuss their research into combatting obesity using various new therapies.
#ExpertAnswers: Michael Czech on CRISPR-Enhanced Adipocyte Browning
In this episode of Expert Answers, Dr. Michael Czech discusses a novel CRISPR-based cell therapy which enhances adipose tissue "browning" as a treatment for metabolic disease.
Ecophysiological Impacts of Climate Change: Performance, Fitness and Extinction
Join Caroline Williams, PhD and Eric Riddell, PhD as they discuss their research involving climate change and the ecophysiological effects of changing global temperatures on organismal biology and survival.
Compound Delivery, PK-PD, & Validation Studies in Oncology Research
Dr. Christian Schnell describes his work involving implantable infusion pump studies in rodents and the advancement of pharmacological interventions in oncology research.
Quality, Quantity and Timing: Regulating Healthspan and Lifespan With Diet
Join Dudley Lamming, PhD for a deep dive into his research involving how diets can affect metabolic health and longevity.
#ExpertAnswers: Matt Kaeberlein on Aging Science
Dr. Matt Kaeberlein, a Professor at the University of Washington School of Medicine, answers questions from a recent webinar that focused on translational geroscience, the drug rapamycin to target biological aging, and the Dog Aging Project.
Self Head Fixation Training for the Study of Perceptual Decisions in Mice
In this webinar, Andrea Benucci, PhD discusses a setup developed in his laboratory for high-throughput behavioral training of mice based on voluntary head fixation.
From “Artificial” to “Real”: What 24/7 Home Cage Monitoring Teaches Us In Pre-Clinical Neurodegenerative Disease Models
Experts discuss an innovative and scalable home cage monitoring solution called Digital Ventilated Cage (DVC), showing how it can be used to study neurodegenerative diseases and monitor biorhythmicity of small rodents.
#ExpertAnswers: Dee Silverthorn on Teaching Anatomy & Physiology
In this episode of Expert Answers, Dr. Dee Silverthorn answers questions on how the sudden appearance of the global pandemic of COVID-19 provides a unique opportunity to show students science in action.
