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Science News
Meet Alicia Carrillo-Sepulveda, Vascular Physiologist and Rodent Microvascular Surgery Scholarship Recipient
Alicia Carrillo-Sepulveda, PhD, recently won a Kent Scientific scholarship for the Comprehensive Training Program for Rodent Microvascular Surgery at Columbia University! We sat down with Alicia to learn why she applied to this scholarship, what skills she gained from the course, and more.
A Novel Ingestible Biosensor for Intestinal Metabolite Monitoring
De la Paz et al. have developed an ingestible, self-powered, and wireless biosensing capsule that can hopefully be used for the noninvasive diagnosis of gastrointestinal disorders in the future. Recently published in Nature Communications, the authors demonstrated how its real-time performance in a porcine model, which we summarize in this post.
Particulate Matter from Firearms: Lung Toxicity and Respiratory Effects
While health and safety precautions are rightly focused on preventing shooting-related injury and death at firing ranges, heavy metal exposure also poses substantial health risks. Kim et al. recently modeled the acute health effects of particulate matter inhalation from firearm smoke in mice, which we review in this post.
Protocol Preview: a Ferret Model of Respiratory Inflammation
While rodents have long been used to model many human diseases, their anatomical, physiological, and immunological differences from humans cannot be ignored when modeling respiratory inflammation. Recently, Khoury et al. demonstrated how ferrets can be used to model inflammatory respiratory disease and injury, which we review in this blog post.
Are They Born This Way? Beat Synchronization in Rats in Response to Lady Gaga, Mozart, and More
Recently, Ito et al. sought to understand beat synchronization in rats and how it compares to humans, which has not been reported to date. In this blog post, we review their findings and how they contribute to our understanding of cross-species beat synchronization.
Orphan Receptor GPR55: A New Therapeutic Target for Atherosclerosis?
Since the role of GPR55 in adaptive B cell response regulation has not yet been reported in the context of atherosclerosis, Guillamat-Prats et al. have investigated how GPR55 in B cells affects atherosclerosis development. In this blog post, we highlight the main findings from this study, which was published this month in Nature Cardiovascular Research.
Mitochondrial Adaptations and Homeostasis: Student Research from the MHRC
The Muscle Health Research Centre (MHRC) is one of Canada's leading innovators in muscle physiology research. In this blog post, we finish our series of interviews with student researchers at the MHRC and learn more about their research objectives, findings, and goals.
Is DNA Vaccination the Future of Type 1 Diabetes Prevention and Management?
Given the fact that type 1 diabetes can vary considerably between individuals, a precision medicine-based therapeutic approach could revolutionize clinical care. Earlier this year, Postigo-Fernandez et al. evaluated a precision medicine approach to DNA vaccination in a mouse model of type 1 diabetes, which we review in this blog post.
Industry Insights with Crown Bioscience: In Vitro Technologies for Studying the Cancer-Immunity Cycle
In this episode of Industry Insights, Rajendra Kumari, PhD, and Gera Goverse, PhD, from Crown Bioscience answer questions about in vivo, in vitro, and ex vivo technologies and methods that can be used for immuno-oncology research along each step of the cancer-immunity cycle.
Sugar, Spice, and a Troubling Vice: Cardiovascular and Cancer Risk with Artificial Sweeteners
Artificial sweeteners appear to be the perfect solution to many of the health problems associated with high sugar consumption, but two recent publications may change the public's opinion on these sugar substitutes.
Industry Insights with Chris Rand from Aurora Scientific
This episode of Share Science features Chris Rand, MSc, sales and marketing manager at Aurora Scientific. In this interview, Chris shares Aurora Scientific’s history, their journey within the preclinical research world, and their advance into the neuroscience space.
Mitochondrial Contributions to Muscle Weakness: Student Research from the MHRC
The Muscle Health Research Centre (MHRC) is one of Canada's leading innovators in muscle physiology research. In this blog post, we continue our series of interviews with student researchers at the MHRC and learn more about their research objectives, findings, and goals.
Industry Insights with Amy Sheng on Nanobodies
This episode of Share Science features Amy Sheng from Sino Biological, who shares how nanobodies are expected to revolutionize antibody-based drug therapies for a wide range of pathological conditions and especially cancer immunotherapy!
Clearing the Brain Fog: Long COVID and Cognitive Impairment
One common post-COVID symptom is brain fog or "COVID fog," which may affect up to 25% of recovered individuals. Given the global prevalence of SARS-CoV-2 and the detrimental impact of such cognitive impairment, the public health implications are considerable. Fernández-Castañeda et al. recently examined the underlying neurological changes associated with COVID fog, which we review in this blog post.
Fright or Delight? Dopamine-Mediated Fear Response in the Amygdala
Since little is known about how dopamine affects aversive learning in humans, Frick et al. recently sought to describe the role of dopamine in fear memory formation within the human amygdala, which we review in this blog post.