Overcoming Critical Issues in Glioblastoma Multiforme (GBM) Therapeutic Development
This article, originally published on Scientist.com, reviews the current standard of care for glioblastoma multiforme (GBM), challenges in developing accurate preclinical GBM models and effective therapies, and the future of GBM drug discovery.
Functional Ultrasound: Pushing the Boundaries of Neuroimaging
Although ultrasound has been used clinically for decades, advances in its temporal and spatial resolution have opened the door for its use in neuroscience research. In this blog post, we review a very recent and outstanding example of functional ultrasound neuroimaging published in Nature Methods in 2022 (featured image © 2022 Renaudin et al., licensed under CC BY 4.0).
5 Hot Topics in Refinement of Nonhuman Primate Neuroscience Research
Adapted from an article published in Laboratory Animal Science Professional Magazine, this blog entry highlights the importance of nonhuman primates (NHPs) in neuroscience research as well as five recent evidence-based NHP refinement advances in neuroscience.
Extracellular Vesicles as Breast Cancer Biomarkers
Triple-negative breast cancer is particularly aggressive, challenging to treat, and accounts for 15-20% of all breast cancers. In this blog, we review a study published in Nature Communications that examines the transforming growth factor-β targetable signaling pathway, its role in malignant cancer progression and immune suppression, and tumor-derived extracellular vesicles as diagnostic and prognostic biomarkers.
Industry Insights with Yuning Chen on Recombinant Proteins
This episode of Share Science features Yuning Chen from Sino Biological, who provides insights into their extensive library of recombinant virus proteins, as well as the importance and value of these high quality reagents!
Talking Real Science with Wendy Riggs
This episode of Share Science features Wendy Riggs, MS, an associate professor of biology at the College of the Redwoods in California. In an earlier webinar, Wendy shared how to adapt classrooms into an online environment, which she dives deeper into in this interview.
Combination Therapy for Cancer Treatment
The combination of anti-cancer drugs, or combination therapy, has been hailed as a “cornerstone of cancer therapy” since it targets key pathways synergistically, thereby enhancing efficacy compared to monotherapies. This blog takes a look at a recent publication in Nature, which reported the effects of 2025 pairwise drug combinations in breast, colon, and pancreatic cell lines.
Discovering a Novel Therapy for Urinary Tract Infections
Originally published on Scientist.com, this article provides an overview of antimicrobial therapies, antimicrobial resistance, and advantages of in silico methods for drug discovery.
Inhalable COVID-19 Vaccines: Recent Findings and Breakthroughs
Given that SARS-CoV-2 is primarily transmitted through respiratory droplets, with respiratory mucosa being the main viral entry route, is intramuscular administration the most effective vaccine delivery method to fight COVID-19? In this blog post, we have reviewed one recent study that reported the design and preclinical testing of an inhalable, exosome-based COVID-19 vaccine.
Does Diabetes Promote COVID-19, or Does COVID-19 Promote Diabetes?
During the COVID-19 pandemic, many of those living with diabetes were required to follow strict guidelines to protect themselves against infection as they were at high risk of morbidity and mortality. This blog takes a look at the links between angiotensin-converting enzyme 2 (ACE2) expression and diabetes, as well as incident diabetes and long COVID.
Cell Painting: The Colorful Future of Drug Discovery
A panel Q&A originally published on Scientist.com that introduces cell painting and highlights its value in preclinical and early drug discovery programs.
Alzheimer’s Disease: Recent Research & Therapeutic Advances
A review of Alzheimer's disease pathology, conventional treatments and their limitations, as well as emerging and potential therapies including monoclonal antibodies, metabolic therapies, and stem cell therapies.
Real-World Data for Mental Health – Understanding Outcomes and Unlocking Pathways to More Precise Treatments
Real-World Data for Mental Health – Understanding Outcomes and Unlocking Pathways to More Precise Treatments OM1 was [...]
Unlocking the Value of Real-World Data to Provide Real-World Care
Unlocking the Value of Real-World Data to Provide Real-World Care For this tHEORetically Speaking video interview, Mary Tran, [...]
Differentiate Your Product From the Competition: Give Payers the Insights They Need
Differentiate Your Product From the Competition: Give Payers the Insights They Need In this competitive pharmaceutical [...]
Recent Advances in Anti-Obesity Pharmacological Research
A review of current obesity treatments and their limitations, the need for animal models in obesity research, and emerging anti-obesity medications including incretin-based therapies, mitochondrial uncouplers, and various phytochemicals.
Women in STEM: Celebrating Our Incredible Female Presenters
Here at InsideScientific, we are fortunate to work very closely with intelligent, talented women in the fields of neuroscience, cardiovascular research, muscle physiology, immunology, metabolic function and obesity, pharmacology, cancer, and respiratory science. In honor of International Women's Day, we would like to not only recognize these incredible presenters, but also celebrate their immense successes and contributions to their respective fields.
Milestones and Recent Advances in HIV Research
In honor of World AIDS Day, InsideScientific has set out to provide information on the historical significance of HIV and AIDS, recent advances in anti-HIV therapy, and the impact that COVID-19 has had on HIV testing, diagnosis and treatment around the world.
Noldus Early-Career Software Grant
Noldus Early-Career Software Grant Noldus Information Technology is seeking proposals from North American researchers from all disciplines of [...]
Alzheimer’s & Brain Awareness Month 2020
Image source: Alzheimer’s Association @alzassociation June is Alzheimer’s and Brain Awareness Month! At InsideScientific, we are proud to [...]
White Paper – Advancing Cancer Treatments with ALZET® Osmotic Pumps
Success is in the delivery. This white paper from ALZET reviews applications and benefits of osmotic pumps for [...]
Purple Day 2020
Purple Day for Epilepsy awareness was started by a young Canadian back in 2008 with the goal of spreading awareness [...]
Industry Interview – Talking Neuroscience with Leonard Khiroug
Scientific progress depends on constant innovation and the development and application of novel tools to push the [...]
World Obesity Day 2020
Obesity is now a global epidemic – with over 650 MILLION sufferers worldwide. While there is still much to [...]
#WomenInSTEM – Celebrating Our Incredible Female Presenters
The gender gap in Science has been widely recognized and much effort is going into encouraging girls and young [...]
