Advertisement

Microbiology & Immunology

Microbiology & Immunology

  • CrownBio Cancer-Immunity Cycle Blog FI

The Cancer-Immunity Cycle: Research Solutions for Preclinical Immuno-Oncology

News, Scientific Articles|

Cancer immunotherapy has undoubtedly expanded the cancer treatment landscape and improved patient outlook, which can in part be attributed to the recognition of the importance of the cancer-immunity cycle as a whole. In this blog, we provide an overview of the cancer-immunity cycle and highlight some preclinical models that can facilitate cancer immunotherapy research.

  • HSV Skin-on-chip FI

Skin-on-Chip for Preclinical Herpes Disease Modeling

News, Scientific Articles|

Organs-on-a-chip are attractive alternatives for bridging the translational gap between preclinical and clinical stages in vaccine development, particularly for herpes simplex virus (HSV). In this blog post, we review an article from Nature Communications on a skin-on-chip device for modeling HSV infection, as well as evaluating immune responses and antiviral drug efficacy (featured image © 2022 Sun et al., licensed under CC BY 4.0).

Extracellular Vesicles as Breast Cancer Biomarkers

News, Scientific Articles|

Triple-negative breast cancer is particularly aggressive, challenging to treat, and accounts for 15-20% of all breast cancers. In this blog, we review a study published in Nature Communications that examines the transforming growth factor-β targetable signaling pathway, its role in malignant cancer progression and immune suppression, and tumor-derived extracellular vesicles as diagnostic and prognostic biomarkers.

  • Cancer cells

Combination Therapy for Cancer Treatment

News, Scientific Articles|

The combination of anti-cancer drugs, or combination therapy, has been hailed as a “cornerstone of cancer therapy” since it targets key pathways synergistically, thereby enhancing efficacy compared to monotherapies. This blog takes a look at a recent publication in Nature, which reported the effects of 2025 pairwise drug combinations in breast, colon, and pancreatic cell lines.

  • Exosome secretion from cells

Inhalable COVID-19 Vaccines: Recent Findings and Breakthroughs

News, Scientific Articles|

Given that SARS-CoV-2 is primarily transmitted through respiratory droplets, with respiratory mucosa being the main viral entry route, is intramuscular administration the most effective vaccine delivery method to fight COVID-19? In this blog post, we have reviewed one recent study that reported the design and preclinical testing of an inhalable, exosome-based COVID-19 vaccine.

  • Talking Real Science with Gwen Randolph

Talking Real Science with Gwen Randolph

This episode of #ShareScience features Gwen Randolph, PhD. She is passionate about the role of women in science, and she shares her personal experiences and passions as both a scientist and as a woman in the field of immunology.

Go to Top