What can biological age tell us about our health? Is it a fixed number, or can it be reduced? A recent study from Poganik et al. investigates the fluctuations in biological age in response to physiological stress.
Join Dudley Lamming, PhD an Associate Professor at the University of Wisconsin-Madison, as he answers questions from a recent webinar that focuses on his research involving how diets can affect metabolic health and longevity.
In this episode of Expert Answers, Dr. Jack Guralnik and Dr. Charlotte Peterson answer questions about sarcopenia, the physiological mechanisms underlying the disease, and the current avenues of treatment and assessment.
Dr. Janos Groh discusses how neuroinflammation amplifies neural damage and disease outcome in models of various disorders, and the value of monitoring the retinotectal system to assess neural disease progression and associated treatment efficacy.
Dr. Matt Kaeberlein, a Professor at the University of Washington School of Medicine, answers questions from a recent webinar that focused on translational geroscience, the drug rapamycin to target biological aging, and the Dog Aging Project.
Experts discuss an innovative and scalable home cage monitoring solution called Digital Ventilated Cage (DVC), showing how it can be used to study neurodegenerative diseases and monitor biorhythmicity of small rodents.
In this webinar, Dr. Joy Wu will review the pathophysiology of bone loss with aging, in particular the imbalance between bone formation by osteoblasts and bone resorption by osteoclasts. She will discuss stem cell sources of osteoblasts, anabolic signaling pathways, and targeting inflammation and senescence.
Dr. Charlotte Peterson and Dr. Jack Guralnik will discuss the challenges of sarcopenia. They will define the disease and provide an in depth overview of the underlying mechanisms of pathology. They will then share some potential therapeutic interventions and disease outcomes for patients.
During this webinar, Dr. Matt Kaeberlein provides an overview of translational geroscience, which he believes will become the paradigm for the practice of medicine in the 21st century. He also discusses his recent work with one such intervention, the drug rapamycin, and its potential to enhance healthspan in companion dogs and people.