While rodents have long been used to model many human diseases, their anatomical, physiological, and immunological differences from humans cannot be ignored when modeling respiratory inflammation. Recently, Khoury et al. demonstrated how ferrets can be used to model inflammatory respiratory disease and injury, which we review in this blog post.
Since the role of GPR55 in adaptive B cell response regulation has not yet been reported in the context of atherosclerosis, Guillamat-Prats et al. have investigated how GPR55 in B cells affects atherosclerosis development. In this blog post, we highlight the main findings from this study, which was published this month in Nature Cardiovascular Research.
Experts discuss how automated microscopy and image analysis can quantify critical markers of infection and describe the insight provided by microscopy in the context of SARS-CoV-2 infection and inflammation.
Dr. Janos Groh discusses how neuroinflammation amplifies neural damage and disease outcome in models of various disorders, and the value of monitoring the retinotectal system to assess neural disease progression and associated treatment efficacy.
Dr. Sophie Pezet and Dr. Benjamin Vidal discuss methodology, applications and new possibilities enabled by functional ultrasound (fUS) imaging, with a focus on chronic pain and neuropharmacology research.